NASA Astronaut Kate Rubins, Pioneer of DNA Sequencing in Space, Retires

August 05, 2025

NASA astronaut and microbiologist Kate Rubins, the first person to sequence DNA in space, has retired after 16 years with the agency.

Rubins made history in 2016 during her first mission aboard the International Space Station (ISS) when she successfully sequenced DNA in microgravity using a handheld device. The achievement proved that astronauts could identify microbes, monitor crew health, and even diagnose illnesses while in orbit — a critical capability for future missions to the Moon and Mars, where rapid medical support from Earth won’t be possible.

As part of Expeditions 48/49, Rubins not only sequenced DNA but also contributed to more than 275 scientific experiments, from cell biology to biomedical hardware. Her work demonstrated that molecular biology techniques, once thought too delicate for space, could be adapted to microgravity. This breakthrough opened the door to in-flight genetic analysis, long-duration cell studies, and new diagnostic tools for astronauts.

Rubins returned to space in 2020 for Expeditions 63/64, continuing her research and expanding DNA sequencing applications for space medicine. Her work showed that astronauts could monitor both human health and microbial environments aboard spacecraft, a vital step in preparing for long-term deep-space exploration.

“Kate’s pioneering work with DNA sequencing has transformed what’s possible in space biology,” said Steve Koerner, acting director of NASA’s Johnson Space Center. “Her legacy will continue to guide the future of astronaut health and research beyond Earth.”

Rubins spent a total of 300 days in orbit and completed four spacewalks during her NASA career.

SOURCE: https://www.nasa.gov/news-release/nasa-astronaut-kate-rubins-first-to-sequence-dna-in-space-retires/ 

CREDITS: NASA