Reduced serotonin levels in long COVID-19 Patients could cause neurocognitive difficulties

October 22, 2023

A novel study published in Cell, by a team led by scientists from the University of Pennsylvania showcases that the deficit of peripheral serotonin caused by long Covid explains the neurocognitive impairments people experience, also known as “brain fog”.

Moreover, these processes associate exaggerated blood clotting and autonomic dysfunction leading to diminished ability of controlling heart rates or blood pressure. 

“We found that it’s really across the board that these decreases of serotonin are noted, so it’s not only in those with neurocognitive effects, but also with pulmonary effects and cardiovascular dysfunction,” Benjamin Abramoff, director of Penn Medicine’s Post-COVID Assessment and Recovery Clinic, said. “It seems to be a universal phenomenon.”